Recent studies have revealed that KRT17 can inhibit tumor cell proliferation, migration and invasion in malignant tumors by regulating the Akt/mTOR pathway, glucose uptake [41], Wnt signaling pathway, epithelial-mesenchymal transition (EMT) [42] and mTOR/S6K1 signaling pathway [43]. The gene discussed is RPS6KB1; the disease is cancer.