In fact, the transcriptomic analysis of the human GBM cases of the TGCA RNASeq dataset showed the GPM-GBM subtype had upregulation of SOD2 and genes related to the TLR4 signaling pathway, including CXCL8, in comparison to the MTC-GBM subtype. This evidence concerns the gene TLR4 and medullary thyroid gland carcinoma.