ITGA5 has been reported to be overexpressed in human mesenchymal stem cells (hMSCs)-treated HCC, and short interfering RNA against ITGA5 blocks the hMSCs-induced migrative and invasive abilities of HCC cells, emphasizing the crucial role of ITGA5 in hMSCs-induced tumor metastasis [56]. Here, ITGA5 is linked to hepatocellular carcinoma.