The typical clinical characteristics of MWS include: onset from infancy or early childhood, repeated intermittent fever without specific inducing factors (not closely related to cold exposure), accompanied by urticarial-like rash, joint pain, headache, conjunctivitis, etc., and the elevated systemic inflammatory indexes (leukocyte count, neutrophil count, CRP, SAA, ESR, etc.). The gene discussed is CRP; the disease is conjunctivitis.