Among 103 trauma patients, 40 patients were excluded from the study: 33 patients due to factors that may affect NT pro-BNP, including intracranial hemorrhage (N = 13), previous myocardial infarction (N = 1), previous coronary artery stent insertion (N = 2), congestive heart failure (N = 1), arrhythmia (N = 3), renal disease (N = 3), hepatic disease (N = 2), severe active bleeding (N = 3), and old age (> 80 years) (N = 5). This evidence concerns the gene NPPB and liver disorder.