This study showed that cell apoptosis was reduced resulting in increased proliferation and viability rates of C6 glioma cells when exposed to NaHS suggesting that p38 MAPK/ERK1/2-COX-2 pathways are involved in NaHS-induced cancer cell proliferation and anti-apoptosis in C6 glioma cells [60]. Here, MAPK3 is linked to central nervous system cancer.