BCL2L1 and candidiasis: This is because candida infection causes cell death by inducing apoptosis in epithelial cells and inhibiting antiapoptotic proteins, such as BD2 and Bcl XL, in macrophages and neutrophils.11Increased candidalysin concentration causes greater epithelial cell necrosis by attacking mitochondrial function, which leads to decreased metabolic activity and adenosine triphosphate and increased intercellular reactive oxygen species, and the induction of necrosis.15