IL17A and hyperinsulinemic hypoglycemia, familial, 4: The occurrence of isolated CMC in patients with autosomal dominant (AD) IL-17F deficiency or inborn errors of the IL-17-responsive pathway, such as AR IL-17RA, IL-17RC, and ACT1, and AD JNK1 deficiencies, revealed the essential role of IL-17A/F in mediating mucocutaneous immunity to Candida albicans (C. albicans) (41–45).