Others, such as Wesolowski et al., have characterized the immunogenic characteristics of tumor cells by evaluating their expression of these receptors, similar to Liang et al. [46] who found a decrease in the number of patients with tumors positive for total PD-1 and PD-L1 (both tumoral and stromal), Sarradin et al. [47] reported a significant decrease in stromal LAG3 expression after NAC treatment. The gene discussed is CD274; the disease is neoplasm.