However, an uncontrolled prospective case series Sweden study published in 2000 consisting of 7 patients with MCD, MN, and IgA nephropathy conversely showed that LDL-A therapy was ineffective in reducing nephrotic range proteinuria even though a small increase in serum albumin and a significant decrease in serum cholesterol, apo B and plasma Lp9a levels were noted [43]. The gene discussed is ALB; the disease is IgA glomerulonephritis.