FGA and human African trypanosomiasis: FGA is a structural component of the extracellular matrix, while ALB is involved in oxygen binding; IL10 in African trypanosomiasis signaling and the malaria signaling pathway, and REN in the renin angiotensin system signaling pathway (see Figures 6A, B, Supplementary Figure S3 and Supplementary Tables S7–S10 for details).