PTEN and gastric cancer: The GX1-modified liposomes have been used to treat gastric cancer, such as GX1-modified liposomes encapsulating PTX (GX1-PTX-NLCs) and GX1-mediated anionic liposomes carrying adenoviral vectors integrating with the tumor suppressor gene of PTEN (GX1-Ad5-AL), which all promoted the cellular uptake by HUVEC cells, enhanced the inhibition of HUVEC cells and significantly suppressed the migration of gastric cancer cell in vitro (Xiong et al., 2015; Jian et al., 2020).