KCNQ1OT1 and colorectal carcinoma: Four lncRNAs, including LINC00355, KCNQ1OT1, LINC00491, and HOTAIR, were found in the probiotic and pathobiont environments while two lncRNAs, including LINC00355 and KCNQ1OT1, were found in the pathogenic environment, according to Tan et al. Patients with CRC who express these lncRNAs strongly have poor prognostic value (Tsai et al., 2020).