In this study, tumor size (P=0.023), low levels of albumin (P=0.024), lymphocyte to monocyte ratio (P=0.044) were independent risk factors for LNM, with age (P=0.072) and white blood cells (P=0.055) (WBCs) slightly greater than 0.05, probably due to the small sample size in this experiment. This evidence concerns the gene ALB and neoplasm.