Knockdown of C/EBPβ in mouse mammary tumor 4T1 cells results in increased expression of various chemokines such as in CCL6, CCL7, CCL8, CCL12, CCL27, CCL28, and CXCL16 expression, although whether C/EBPβ directly inhibits these chemokines was not addressed (24). This evidence concerns the gene CEBPB and breast cancer.