PARP1 and cancer: In addition, we found statistical support for aBRCA1 andPARP1/2 SLIs by the SoF inference procedure [Figures 3A(iii) and 3B(iii,iv)] (P < 0.05), whereas the FunEx module found statistical support for aBRCA1-PARP1 SLI [Figure 3A(iv)] (P < 0.01), but not for aBRCA1-PARP2 SLI, based on the cancer cell line gene-dependency CRISPR or shRNA datasets.