VCAM1 and metabolic disease: Another pro-inflammatory adipokine, resistin was found to promote the expression of many pro-inflammatory cytokines (such as TNF-α and IL-6) (27, 50) and adhesion molecules [such as ICAM-1 and vascular cell adhesion molecule 1 (VCAM-1)] (27) in many diseases, such as vascular diseases (72), metabolic disorders (73), and cystic fibrosis (74).