Further, we found that the expression of IGF2BP3 was positively related to the MSI in 6 cancers, including LUSC, BLCA, TGCT, ESCA, SARC, and COAD, but had a negative correlation with MSI in SKCM, THCA, HNSC, and DLBC (Supplementary Figure 8B). Here, IGF2BP3 is linked to cancer.