IGF2BP3 and melanoma: Specifically, previous evidence has indicated that IGF2BP3 plays a crucial role in human cancer development, such as breast cancer (10, 22), mesothelioma (11), colon cancer (15, 19), lung cancer (18), melanoma (13), nasopharyngeal carcinoma (NPC) (14), and hepatocellular carcinoma (HCC) (20).