ROC curve and Survival curve in pan-cancer plotted by Kaplan-Meier estimate revealed that IGF2BP3 had a certain accuracy (AUC>0.7) in predicting 24 cancer types, especially had a strong predictive power (AUC>0.9) in predicting LAML, GBM, UCS, LUSC, STAD, OV, CHOL, and ESCA. The gene discussed is IGF2BP3; the disease is cancer.