As shown in Figures 4A–H, IGF2BP3 has an exact accuracy (AUC > 0.7) in predicting 24 cancer types, and even exceeded 0.9 in 8 cancers including LAML (AUC = 1.0), GBM (AUC = 0.998), UCS (AUC = 0.983), LUSC (AUC = 0.939), STAD (AUC = 0.936), OV (AUC = 0.927), CHOL (AUC = 0.926), and ESCA (AUC = 0.920) (Supplemental Table 2), which had high diagnostic value. Here, IGF2BP3 is linked to cancer.