BRCA2 and pachyonychia congenita: Furthermore, the other germline mutations in mismatch repair genes (MLH1, etc.), the partner and localizer of BRCA2 (PALB2), cationic trypsinogen-gene (PRSS1), serine/threonine kinase 11 (STK11), ATM serine/threonine kinase (ATM), and breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) are correlated with a high risk of PC (14–16).