In our study, we analyzed the relationship between MAGs and the prognosis of patients with DLBCL in the GEO database and established a MAG prognostic model containing 14 genes (CCDC78, CD300LG, CTAG2, DYNLL2, MAPKAPK2, MREG, NME8, PGK2, RALBP1, SIGLEC1, SLC1A1, SLC39A12, TMEM63A, and WRAP73) that showed high predictive accuracy. Here, SLC1A1 is linked to diffuse large B-cell lymphoma.