NHSL3 and neoplasm: We conducted a comprehensive analysis of the value of KIAA1522 in HCC prognosis and tumor immune infiltration using RNA sequencing data retrieved from the TCGA database, along with receiver operating characteristic (ROC) curve, differentially expressed gene (DEG) analysis, gene ontology (GO) term analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, single-sample gene set enrichment analysis (ssGSEA), gene set enrichment analysis (GSEA), Kaplan–Meier survival analysis, and logistic and Cox regression analysis.