Logistic regression analysis showed that KIAA1522 was significantly correlated with the T stage (P=0.003), histologic grade (P < 0.001), AFP (P < 0.001), tumor status (P=0.022),and had a trend of correlation with pathologic stage (P=0.088) and vascular invasion (P=0.082) (Table 2). This evidence concerns the gene AFP and neoplasm.