Moreover, the dual role of DDX3 have been reported in same type of cancer, including breast cancer (124, 167–169), hepatocellular carcinoma (170, 171), lung cancer (142, 172), colorectal cancer (70, 173, 174), and head and neck squamous cell carcinoma (69, 175, 176). The gene discussed is DDX3X; the disease is colorectal cancer.