Median circulating chemerin was more than two-fold higher in CKD patients (542.2 ± 98.1 μg/l) compared with control patients (254.3 ± 88.7 μg/l) (p<0.001). There was no significant difference between males and females or patients with or without T2DM. Here, RARRES2 is linked to type 2 diabetes mellitus.