Inflammation, along with the modulation of endothelial damage characteristic of adipokines, has been recently confirmed in the kidneys of patients and rats with diabetic nephropathy (DN), where the expression of chemerin, chem1, and inflammatory factors was significantly increased in DN, implicating chemerin as an active agent in the pathophysiology of glomerular endothelial cell inflammation (30). Here, RARRES2 is linked to liver dysplastic nodule.