The top 10 DEPs (named in KO (KEGG Ontology)) were statistically significant as candidate biomarkers to distinguish VD from AD or NC (shown in Table 3; Figure 7), including PLOD3, SDCBP, SRC, GPRC5B, TSG101/STP22/VPS23, THY1/CD90, PLCD, CDH16, NARS/asnS, AGRN. The gene discussed is PLOD3; the disease is Alzheimer disease.