According to KEGG Orthology, we divided the pathways into five classes, including proliferation (e.g., cell cycle and DNA replication), immune system (e.g., natural killer cell-mediated cytotoxicity and chemokine signaling pathway), signal transduction (e.g., PI3K/Akt signaling pathway and NF-κB signaling pathway), cancer overview (e.g., proteoglycans in cancer and chemical carcinogenesis) and metabolism (e.g., oxidative phosphorylation and pyruvate metabolism). The gene discussed is NFKB1; the disease is cancer.