NEGR1 and depressive symptom measurement: The second region with significant SNPs was on chromosome 1, and holds expression quantitative trait loci (eQTLs) for neural growth factor 1 (NEGR1), a gene strongly related to various variables related to cognition and socioeconomic status, including cognitive performance and educational attainment (Lee et al., 2018), BMI (Pulit et al., 2019), substance use and protein intake (Liu et al., 2019; Niarchou et al., 2020), and depression symptoms (Baselmans et al., 2019).