This study was performed mainly to summarize the clinical characteristics of sporadic and VHL-related supratentorial hemangioblastoma and explore the differences in clinical characteristics between cystic and solid tumors in supratentorial hemangioblastoma in order to enrich the current evidence of biological and clinical features and further optimize the management of intracranial hemangioblastoma, especially supratentorial hemangioblastoma. The gene discussed is VHL; the disease is hemangioblastoma.