NOS3 and pulmonary hypertension, primary, 1: As shown in Figure 6, Pik3c2a, Akt1, eNOS, Hspa8, Dnajal, and Arntl were downregulated, and Dbp, Rasd1, Ugt1a1, and Aldh1a3 were upregulated in the PHT group compared to the controls.