SRCAP and colorectal carcinoma: In addition, ΔNp63α can participate in the formation of another CRC called SRCAP (SNF2-related CBP Activator Protein), which belongs to the INO80 family and facilitates the substitution of histone H2A to its variant H2A.Z in nucleosomes; as a result, anti-proliferative genes (e.g., SAMD9L, ZHX2, and IGFBP3) are repressed at transcription level [108–110].