On the other hand, we could detect a stronger upregulation in COVID-19 of complement proteins C9, CFD, fibrinogen proteins FGA, FGB, FGG and some other proteins (AMBP, ITIH4, leucine-rich alpha-2-glycoprotein LRG1, alpha-1-acid glycoproteins ORM1, ORM2, SERPINA1, SERPINA3, SERPINF2, SERPING1, SGCE, PROCR, RBP4). The gene discussed is SGCE; the disease is COVID-19.