The results of earlier studies also reported that melatonin may act as a tumor inhibitor molecule in glioblastoma stem-like cells by recruiting the EZH2-related axis, which could involve multiple pathways including EZH2‐NOTCH1 [202] and AKT‐EZH2‐STAT3 signaling [203]. The gene discussed is EZH2; the disease is glioblastoma.