To further gain insight into the function of PHF5A in medulloblastoma, we first verified that downregulation of ABL1 reduced pY36-PHF5A level in centrosome (Fig. S6A), and pY36-PHF5A decreased the protein level of CEP250 in Daoy cells (Fig. 7A and Fig. S6B). Here, CEP250 is linked to medulloblastoma.