Previous GWASs of PD in European ancestry, East Asian, and Latino populations comprising more than one million samples have identified over 80 risk loci with more than 90 independent risk variants, including in SNCA, LRRK2, MAPT, BST1, GCH1, VPS13C, and TMEM1758–10. The gene discussed is LRRK2; the disease is Parkinson disease.