HAVCR2 and non-small cell lung carcinoma: Moreover, distal metastasis was present in a lower percentage of NSCLC patients who were smokers and HAVCR2 rs10057302 carriers of CA genotype than patients with CC genotype irrespective of smoking status (CA smokers 16.67% vs. CC Non-smokers 36.36%, CC smokers 32.53%; P = 0.009) (Table 3).