MAPT and focal epilepsy: In a subsequent study of 60 consecutive patients who had undergone surgical treatment for drug-resistant focal epilepsy between 18 and 45 years of age, median age at resection 29.5 years, none of the patients had pathological findings characteristic of CTE (0%), although 23 patients (38%) demonstrated non-specific p-tau pathology, including neurites, pretangles, NFTs, subpial tau, and glial tau [109].