NLRP3 and inflammation: Treatment with A68,930 (D1-like agonist) inhibited NLRP3 activation in doxorubicin-treated murine cardiac myoblasts, as well as in mice with cardiac inflammation induced by doxorubicin, CNS inflammation induced by intracerebral hemorrhage, and acute kidney injury caused by renal ischemia/reperfusion (Wang, Nowrangi et al., 2018; Cao et al., 2020; Liu, Jin et al., 2021).