To investigate the mechanistic basis for PI4K2A’s positive correlation with EMT, we used a panel of human lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC) cell lines that have been classified as epithelial or mesenchymal and in which high ZEB1 levels maintain a partial EMT (22, 24). This evidence concerns the gene ZEB1 and lung adenocarcinoma.