At the same time, they also evaluated the correlation between ctDNA and tumor recurrence and described that the sensitivity and specificity of postoperative ctDNA levels in predicting tumor recurrence were 100% and 83.3%, respectively, with a Kappa index of 0.769; these findings signal that there is a significant agreement between ctDNA detection and tumor recurrence after surgery, and ctDNA is superior to CA125 or HE4 in detecting tumor recurrence. The gene discussed is WFDC2; the disease is neoplasm.