SAMD9 and esophageal squamous cell carcinoma: Interestingly, the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis using RNA sequencing dataset of primary ESCC samples (Figure 1a) showed that Wnt/β‐catenin pathway, EMT, and angiogenesis are essential factors for postoperative metastatic recurrence of ESCC (Figure 3c), suggesting that SAMD9 might promote ESCC metastatic recurrence via stimulating Wnt/β‐catenin pathway, angiogenesis, and EMT.