MYH9 and cancer: Myosin‐9 (YH9) is a non‐muscle myosin heavy chain IIA involved in the regulation of cell migration.[7] Studies have shown that MYH9 is aberrantly upregulated and it enhances cancer stemness in gastric[8] and liver cancers.[9] Importantly, cancer stemness is a crucial factor for cancer metastatic recurrence.[10] Upregulated MYH9 expression and its correlation with metastasis in ESCC was reported previously.[11] These findings suggest that MYH9 might promote ESCC metastasis by enhancing cancer stemness, but whether MYH9 promotes ESCC progression through cancer stemness has not been reported.