PHF6 and neoplasm: We further studied the role of PHF6 in shaping the tumour immune microenvironment in UCEC because (i) high expression of PHF6 occurred in UCEC tissues (Figure 1); UCEC patients with PHF6 mutations or UCEC patients with lower expression of PHF6 had a favourable prognosis (Figure 1); and (ii) the expression level of PHF6 may reflect the status of T cells infiltration in UCEC (Figures 3 and 4).