CAMK2G and cocaine dependence: Since phosphorylation of GABAB1 by the phosphorylation of CaMKII (pCaMKII) plays a key role in the aberrant decreased abundance of GABABR under pathophysiological conditions excluding cocaine addiction, while our previous studies shown cocaine may increase locomotor activity by recruiting to dopamine D3 receptor (D3R) via the phosphorylation of CaMKII.15