REN and aortic stenosis: <h4>Purpose</h4>The present study aimed to investigate the association of renin-angiotensin system inhibitors (RASi) with short- and long-term mortality in patients with aortic stenosis (AS).<h4>Methods</h4>A systematic search was performed in PubMed, Embase, and Cochrane library databases for relevant studies published before March 2022.