The expression level of Kv10.2 was significantly reduced in the hippocampus of VPA-induced rats (a model of ASD), and autism-like behaviors, such as stereotypical behaviors and impaired social and exploratory abilities, were effectively ameliorated after upregulation of Kv10.2 expression by lentivirus injection in the hippocampus (6). Here, KCNH5 is linked to autism.