ARMS2 and age-related macular degeneration: In addition, with the help of iMGs, Micklisch et al. discover that human microglia express the age-related maculopathy susceptibility 2 (ARMS2) transcripts which can cooperate with properdin and intensify the ability of complement activation to eliminate apoptotic and necrotic cells and its polymorphism is associated with AMD susceptibility (Micklisch et al., 2017).