CD40LG and cancer: Figure 6 shows the correlation between HN1 and ICB efficacy-related genes (Figure 6(a) is box plot of spearman r value; Figure 6(b) is correlation map). Figure 6(a) shows that HN1 expression is positively correlated with LDHA, LDHB, TNFSF9, TNFRSF18, IFNG, etc., while negatively correlated with JAK1, JAK2, CD40LG, etc., indicating the possibility that HN1 might serve as a prognostic biomarker or potential therapeutic target for cancer immunotherapy. Figure 6(b) is the correlation map of HN1 and ICB efficacy-related molecules.