Similar results were seen with the correlating proteins, TNFRSF9 and sCD5, with significantly elevated concentrations in patients with ongoing 1st line DMD treatment compared to both patients with second-line DMD treatment (TNFRSF9: P < 0.001; sCD5: P < 0.001) and untreated (TNFRSF9: P < 0.01; sCD5: P < 0.05). The gene discussed is SCD5; the disease is Duchenne muscular dystrophy.