NDP and infection: However, the distinct responses in these extensive quantitative assays performed with a wide range of doses of α-2,3 S and α-2,3,6,8 NAs indicate that these virions use different types of sia glycans for binding and infection, which may account for the relatively higher tropism of Nd for the U373MG cells (Figure 3) since GBM cell surfaces express high levels of aberrant sialylated glycolipids (Yeh et al., 2016; Fabris et al., 2017).