MMP11 and cancer: According to an analysis of MMP11 gene expression in various cancer types using the Oncomine database, MMP11 was highly expressed in bladder, breast, cervical, colorectal, esophageal, gastric, head, and neck tumors, kidney, leukemia, lung, lymphoma, melanoma, ovarian, and pancreatic cancers when compared to normal tissues (Figure 1A) (high expression in red, low expression in blue).