We similarly analyzed the differences in immune cell infiltration of tumor tissue between the EGFR-mutant (red) and EGFR-wild (blue) groups in LUAD, showing that compared to the EGFR-wild group, patients in the EGFR-mutant group had a higher proportion of T cell CD8+ (P < 0.0001), T cell follicular helper (P < 0.05), NK cells activated (P < 0.05), Mast cells activated (P < 0.01) were reduced, and the percentage of macrophage M2 (P < 0.05), Myeloid dendritic cells resting (P < 0.05), and myeloid dendritic cells activated (P < 0.05) were all increased (Figure 5B). This evidence concerns the gene EGFR and neoplasm.