IGHE and systemic lupus erythematosus: In a study of 92 SLE patients, the immunoblotting of sera obtained from 29 patients positive for antinuclear IgE antibodies revealed IgE reaction with nucleosomes (79.3%), dsDNA (48.3%), SS-A/Ro (48.3%), SS-B/La (18.7%), Sm (48.3%) and RNP (62.1%) (Atta et al., 2010).