NCOA4 and neoplasm: Additionally, Mou et al. (58) found in a 2021 study that the expression level of NCOA4 mRNA in tumor cells of patients with ccRCC was significantly lower than that of normal tissues in TGGA database and GEO database (p = 7.337e-2, p = 4.696e-050.018), which is associated with overall survival (OS) and immune cell infiltration in patients with ccRCC.